nrs12002‎ > ‎

NRS 12, e002 | Figure 6

Wu DY, Ou CY, Chodankar R, Siegmund KD and Stallcup MR (2014) Distinct, genome-wide, gene-specific selectivity patterns of four glucocorticoid receptor coregulators Nucl Recept Signal 12, e003. doi:10.1621/nrs.12002

 




Figure 6. IPA canonical pathway analysis of the TNFR2 pathway. White genes are not regulated by dex. Grey genes are dex-regulated genes with no change in expression in dex-treated cells after coregulator depletion. Blue genes are dex-regulated genes that have lower expression in dex-treated cells after coregulator depletion, with intensity corresponding to degree of down-regulation. Green genes are dex-regulated genes that have higher expression in dex-treated cells after coregulator depletion, with intensity corresponding to degree of up-regulation. Scores representing –log(p-value) from Fisher’s exact test are: 0.62 (CCAR1), 3.74  (CoCoA), 0.71 (CCAR2), 5.11 (ZNF282). The direction of dex regulation of these genes is shown in Supplementary File 1, Supplemental figure S10.