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NRS 13, e004 | Figure 6

Puhl A, Milton F, Cvoro A, Sieglaff D, Campos J, Bernardes A, Filguiera C, Lindemann JL, Deng T, Neves F, Polikarpov I and Webb P (2015) Mechanisms of peroxisome proliferator activated receptor γ regulation by non-steroidal antiinflammatory drugs. Nucl Recept Sig 13, e004. doi:10.1621/nrs.13004


 

Figure 6. Effects of individual NSAIDS on gene expression. The data is presented as a cluster analysis (MultiExperiment Viewer; www.tm4.org/mev/). Genes differentially modulated by rosiglitazone and NSAIDs within the specified functional categories are organized through hierarchical clustering. Red represents gene transcripts with increased, green decreased, and black no changes in expression level. Rosiglitazone and NSAIDs displayed similar pattern of regulation of genes involved in designated biological processes, although rosiglitazone produced a more pronounced response in comparison to NSAIDs. .